IndraLab

Statements

USP13 deubiquitinates STING1. 4 / 5
1 | 4
reach
"The USP family of DUBs is very important, with USP13, USP18, USP20, USP21, USP44, and USP49 shown to mediate the deubiquitination of STING (Chen et al., 2021)."
36579404
reach
"Consistently, reconstitution of USP13 but not USP13 (AE) into Usp13 m/m MEFs inhibited HSV-1-induced ubiquitination of STING (XREF_FIG)."
28534493
reach
"For example, USP13 regulates antiviral responses by deubiquitinating STAT1 and STING (Sun et al. 2017; Yeh et al. 2013) and is related to PTEN and MITF in the modulation of tumorigenesis (Zhang et al. 2013; Zhao et al. 2011)."
36585612
reach
"In addition, USP13 negatively modulates antiviral immunity by deubiquitinating STING, and targeting USP13 consequently triggers STING-interferon signaling and strengthens innate immunity [26]."
36564767