IndraLab

Statements

Hydroxychloroquine inhibits SH2B2. 5 / 5
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"C. Belizna (France) presented the first results on the retrospective part of the Hibiscus Study, i.e., the use of hydroxychloroquine (HCQ) to prevent thrombotic and obstetric relapses in primary APS."
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"These findings suggest that HCQ, in combination with other therapies, can prevent catastrophic APS and improve pregnancy outcomes."
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"On the other hand, in the APS/aPLs subgroup, the risk of preeclampsia reduced by 34% in the HCQ group (n = 179) compared to the control group (n=188), but this result was not statistically significant (RR: 0.66, 95% CI: 0.29–1.54, p = 0.34) without heterogeneity (I = 0%, p = 0.59)."
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"Furthermore, it has been reported that HCQ is able to dramatically reduce the antiphospholipid antibodies levels in obstetrical APS [ 9 ]."
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"HCQ may help reduce the risk for thrombosis and APS-related poor outcomes."
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