IndraLab

Statements

Brompheniramine inhibits KCNH2. 6 / 7
1 2 | 1 2
trips
"Inhibition of HERG current by brompheniramine showed time-dependence."
17516459
reach
"Brompheniramine inhibited HERG current in a concentration dependent manner with the half-maximal inhibitory concentration (IC50) value of 1.7 microm at 0 mV."
17516459
ctd
No evidence text available
17010640
reach
"These results indicate that brompheniramine mainly inhibited the HERG potassium channel through the residue Y652 and F656 and these residues may be an obligatory determinant in inhibition of HERG current for brompheniramine."
17516459
ctd
No evidence text available
17516459
tas
No evidence text available
21185626