IndraLab

Statements

USP1 inhibits dioxygen. 2 / 2

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"The double knockdown of either ITGB4 and PXN or USP1 and VDAC1 combination increases mitochondrial oxygen consumption rate, leading to increased ROS generation resulting ultimately in increased DNA damage."

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"Suppression of ITGB4/PXN or USP1/VDAC1 enhanced the oxygen consumption in mitochondria that resulted in elevated ROS formation and DNA damage."

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INDRA sources:

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IndraLab

Statements

USP1 inhibits dioxygen. 2 / 2

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