IndraLab

Statements

(-)-epigallocatechin 3-gallate inhibits RELA. 13 / 17
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"EGCG treatment sequesters the p65 subunit of transcription factor NF-kappaB in the cytoplasm and inhibits transcriptional activity of the NF-kappaB-driven promoter in response to CpG-ODN."
24971028
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"Epigallocatechin-3-gallate (EGCG), which is the major constituent of green tea, sequestered the p65 subunit of transcription factor nuclear factor-κB in the cytoplasm and inhibited transcriptional activity of the nuclear factor-κB-driven promoter in toll-like receptor-mediated activation, resulting in reduction of inflammatory cytokine production."
30936628
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"Taken together, these results suggest that EGCG reduced PCB 126 mediated induction of p65 and suppressed NF-kappaB signaling via preventing PCB 126 induced p65 nuclear translocation in endothelial cells."
26878794
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"Moreover, EGCG inhibited the activation of NF-kappaB and p65, an upstream regulator of COX-2, in A375 melanoma cells, and treatment of cells with caffeic acid phenethyl ester, an inhibitor of NF-kappaB, also inhibited cell migration."
22022384
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"XREF_BIBR Epigallocatechin-3-gallate (EGCG), a gallic acid ester of catechin, blocks the production of TNF-alpha, IFN-gamma, NF-kB, and p65, which reduces inflammation in the intestinal mucous membrane."
25349576
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"Moreover, EGCG inhibited NF-kappaB p65 activity by modulating the cellular localization of p65 and decreasing the transcriptional regulation of NF-kappaB p65 on Twist1 expression."
25487615
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"EGCG was found to inhibit the activation of NF-kappaB and p65 in a dose dependent manner."
23474498
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"EGCG inhibits the activation of NF-kappaB and p65 in a dose dependent manner."
22022384
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"EGCG also inhibited the upregulation of nuclear factor-kappa B/p65 (NF-kappaB and p65), and induction of cyclooxygenase 2 and inducible nitric oxide synthase."
26198193
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"Moreover, EGCG inhibited NF-kappaB p65 activity by modulating the cellular localization of p65 and decreasing the transcriptional regulation of NF-kappaB p65 on Twist1 expression."
25487615
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"EGCG alone inhibited NF-kappaBp65 and p-c-Jun (Ser 73) effectively."
28532672
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"The TNF-alpha-mediated NF-kappaB (p65) increase in the nuclei was blocked by the treatment of EGCG (XREF_FIG)."
16100442
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"Both erlotinib and EGCG or their combination failed to inhibit p65 and Bcl-2 in M4e cells (XREF_FIG)."
19470788