IndraLab

Statements

STAMBP activates NLRP3. 2 / 2
| 2
reach
"Instead, STAMBP triggers NLRP3 K63-linked polyubiquitination in response to endotoxin, which seems to function as an activating and non-degradative signal for the NLRP3 inflammasome."
33253913
reach
"While STAMBP does not modulate NLRP3 protein abundance, cellular depletion of the deubiquitinase increased NLRP3 K63 chain polyubiquitination resulting in increased NLRP3 inflammasome activation."
33253913