IndraLab

Statements

USP9X leads to the deubiquitination of FBXW7. 3 / 4

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"USP9X inhibits FBXW7 autoubiquitination, thereby reducing the activity of its downstream substrate c-Myc and suppressing tumor formation in mice (Khan et al., 2018)."

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"USP9X antagonized FBW7 ubiquitylation and protected mice from CRC."

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"USP9X antagonized FBW7 ubiquitylation, and Usp9x deletion caused Fbw7 destabilization."

29346117

INDRA sources:

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IndraLab

Statements

USP9X leads to the deubiquitination of FBXW7. 3 / 4

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