IndraLab

Statements


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"17-AAG decreased IKK complex proteins, IKKalpha and IKKbeta."

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"In both H23 and HepG2 cells, the Hsp90 inhibitor 17AAG caused dramatic degradation of RIP1 and IKKbeta, two critical components for TNF-alpha-induced NF-kappaB activation, regardless of the presence of SMC3."