IndraLab
Statements
BRCC3 activates cell population proliferation. 13 / 13
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13
reach
"Besides, BRCC3 could activate NLRP3 inflammasome-dependent pyroptosis (26), which could then promote tumor progression.In conclusion, UCA1 acted as an oncogene in pancreatic cancer by partly regulating miR-582-5p/BRCC3, which promoted cell proliferation, migration, and inhibited apoptosis."
reach
"The comprehensive analysis of the functions of BRCC3, an E3 ubiquitin ligase associated with heightened cell proliferation, ANP32E, which regulates histones, aids in cell adhesion, and promotes the proliferation of TNBC cells, and ANLN, which facilitates cytokinesis and encourages tumor cell proliferation, highlights the critical importance of these genes in the progression of TNBC and establishes them as prospective therapeutic targets."