IndraLab

Statements


USP22 activates miR-34b. 4 / 4
| 4

reach
"To confirm that USP22 is a direct target of miR-34b, we cloned the 3 '-UTR of USP22 into a reporter plasmid downstream of the luciferase gene."

reach
"Overexpression of USP22 attenuates the inhibitory effect of miR-34b on NPCcell proliferation."

reach
"Overexpression of USP22 attenuates the inhibitory effect of miR-34b on NPC cell viability and proliferation, thus confirming our hypothesis that miR-34b inhibits NPC proliferation by downregulating USP22."

reach
"MTT (XREF_FIG), cell cycle (XREF_FIG), and colony formation analyses (XREF_FIG) show that overexpression of USP22 can significantly attenuate the suppressive effect of miR-34b."