IndraLab

Statements


USP37 ubiquitinates CDT1. 2 / 2
| 2

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"USP37 induces deubiquitination of CDT1, whereas a catalytically inactive (C350S) USP37 mutant is unable to ubiquitinate CDT1, further suggesting that USP37 plays a role in CDT1 stabilization."
| PMC

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"In patients with lung cancer who also experienced OSA, IH induced a decrease in the expression of microRNA-320b, with downstream expression of ubiquitin-specific peptidase 37 (USP37) upregulated secondary to IH and USP37 promoting lung cancer progression by mediating the deubiquitination of Cdc10-dependent transcript 1 (CDT1) (98)."