IndraLab

Statements

CALM1 inhibits PDE. 7 / 7
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"The effects of cal- modulin and various phospholipids were tested on the activity of a partially purified phosphodiesterase which had been deactivated by the removal of cal- modulin."
6291552
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"Table 1 shows that inhibition of CAM stimulated PDE activity occurred with levels reduced by 52 and 72%, respectively, for AS-1 and AS-2."
11024266
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"This latter value is similar to the dose required for half- maximal effects of trifluoperazine on inhibition of calmodulin- activated phosphodiesterase [20) and on binding to calmodulin [15]."
6119229
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"* Unit - one unit is defined as 196 inhibition of calmodulin- stimulated phosphodiesterase activity."
6092816
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"The actions of neuroleptic agents on inhibition of calmodulin- activated phosphodiesterase offer exciting new possibilities with regard to understanding the molecular substrates of psychosis."
6267397
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"Moreover, the sulphoxide analogue of prochlorperazine, which is also less potent in inhibiting calmodulin- activated phosphodiesterase (unpublished) was also ineffective in inhibiting prolactin secret[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
6119229
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"Because caM antagonists W-7 and W-13 inhibit PDE activity (IC 50 = 28 mM and 68 mM, respectively), W-7 and W-13 may block IR enhancement of DSB rejoining fidelity by inhibiting Ca 2+ / caM dependent p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
10856832