IndraLab

Statements

USP39 increases the amount of BRCA1. 3 / 3
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"Although, how USP39 modulates BRCA1 mRNA expression as a spliceosome component remains unclear, it is clear that it is not linked to the PAR-dependent USP39 function in DDR."
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"Interestingly, similar to our results, they also found that the level of BRCA1 mRNA is significantly decreased by USP39 depletion (74)."
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"In parallel, we have also shown that USP39 depletion leads to decreased mRNA expression of BRCA1, which might affect the BRCA1 foci formation."
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