IndraLab

Statements

USP43 binds NuRD. 4 / 4
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"The USP43/NuRD complex inhibits the activity of EGFR and AKT, while the EGFR/PI3K/AKT signaling pathway regulates the behavior of USP43."
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"Therefore, it has been established that the USP43/NuRD complex inhibits the growth, invasion, and metastasis of breast cancer cells; thus, USP43 may serve as a suppressor of breast cancer."
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"Histone H2BK120 can be deubiquitinated by the complex of USP43 and NuRD complex and be reactivated."
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"It has been discovered that the USP43/NuRD complex inhibits the expression of numerous cancer-related genes, including the epidermal growth factor receptor (EGFR)."
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