IndraLab

Statements


STUB1 leads to the ubiquitination of KCNQ1. 3 / 3
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sparser
"Engineered CHIP enhanced KCNQ1 ubiquitination, eliminated KCNQ1 surface-density, and abolished reconstituted K + currents without affecting protein expression."

sparser
"The paper not only describes the CHIP-dependent ubiquitination of KCNQ1, but also its ubiquitination by other E3 ligases such as the NEDD4-2 ligase, already shown to ubiquitinate KCNQ1."

reach
"Engineered CHIP enhanced KCNQ1 ubiquitination, eliminated KCNQ1 surface-density, and abolished reconstituted K + currents without affecting protein expression."