IndraLab

Statements


OTUB1 increases the amount of Cyclin. 2 / 2
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"Thereof, the protein level of cyclin E1, a marker and driver of cell proliferation, was suggested to be increased by OTUB1 (39)."

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"As illustrated in Figures 2G and S2E, the knockdown of OTUB1 decreased the expression of the cell cycle promoter cyclin D1 and the anti-apoptotic factor B-cell lymphoma 2 (Bcl2), while increasing the expression of the pro-apoptotic factor Bcl-2-associated X protein (BAX)."