IndraLab

Statements

STAMBP binds MC4R. 2 / 2
| 2
sparser
"By comparison, α–MSH bound to MC4R with a 4.5-fold higher affinity (K d = 11.93 ± 1.23 nM) than LCN2 and competed for binding with LCN2 with aK i of 12.63 ± 1.10 nM ( xref and xref )."
28273060
sparser
"Together with inhibiting the activity of the POMC/CART neurons through a GABAergic effect (Pu et al., xref ), they release AgRP, a characterized anabolic peptide able to competitively inhibit α–MSH binding to the MC4R (Ollmann et al., xref )."
28690493