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Ato inhibits USP10. 1 / 1

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"Previous reports had suggested that ATO could degrade FLT3 protein by downregulating USP10 to inhibit FLT3-ITD positive cells, but ATO at low concentrations (0.5 microM) failed to downregulate USP10 and could not induce degradation of total FLT3 and modulation of 160KD or 130KD FLT3 (Additional file 1 : Figure S1A, B)."

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Ato inhibits USP10. 1 / 1

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