IndraLab

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Dofetilide increases the amount of KCNH2. 2 / 2

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"The increase in hERG surface expression by dofetilide is consistent with the increased trafficking efficiency observed by Varkevisser et al. (2013) XREF_BIBR."

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reach

"Dofetilide analogues that displayed high channel affinity, mediated by pi-pi stacks and hydrophobic interactions, also restored hERG protein levels, whereas analogues with low affinity were ineffective."

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IndraLab

Statements

Dofetilide increases the amount of KCNH2. 2 / 2

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