IndraLab
Statements
"In contrast, depletion of non-enzymatic components, ATXN7L3 or ENY2, results in increased <span class="match term1">H2Bub1</span>. These observations led us to discover two H2Bub1 DUBs, <span class="match term0">USP27X</span> and USP51, which function independently of SAGA and compete with USP22 for ATXN7L3 and ENY2 for activity."