IndraLab

Statements


DCPIB activates KCNK2. 4 / 4
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"DCPIB, a known specific and potent inhibitor of volume regulated anion channels (VRAC), has been reported to activate TREK1 and TREK2 in astrocytes and in vitro recently."

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"Recently DCPIB was found to activate TREK potassium channels in cultured astrocytes."

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"DCPIB, a prominent inhibitor of VRAC channel, has been recently reported to also significantly activate TREK1 channel."

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"Even more peculiar, DCPIB was found to enhance the activity of the two-pore domain K + channels TREK-1 and TREK-2, in their native environment and after recombinant expression [XREF_BIBR]."