IndraLab

Statements

CYLD decreases the amount of CD274. 3 / 3
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"CYLD knockdown significantly enhanced the expression of PD-L1 in presence of IFN-gamma stimulation in most TET cell lines."
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"CYLD knockdown upregulated IFN-gamma mediated activation of the STAT1 and IRF1 axis, which in turn induced PD-L1 expression."
32738418
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"The mechanisms of miR-588 transfer from macrophage to gastric cancer cells should be confirmed by more complicated investigations in future.Moreover, it has been reported that inhibition of CYLD enhances IFN-γ-regulated PD-L1 expression in thymic epithelial cancer[29]."
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