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USP22 increases the amount of ODC1. 1 / 1
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"Additionally, DHT stimulation in USP22 upregulated cells promoted a ~ 4-fold increase in ODC expression above DHT stimulated conditions (XREF_FIG), which was significantly sustained in LN-USP22 cells upon Casodex treatment (although compared to the AR targets examined in XREF_FIG, Casodex showed a relatively more pronounced inhibitory effect)."