IndraLab

Statements


USP7 is produced. 3 / 3
| 3

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"mmu_piR_037459 overexpression inhibited USP7 protein expression and mmu_piR_037459 knockdown increased USP7 protein expression ( Fig. 4 A and B)."

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"ELISA and Western blotting results indicated that USP7 overexpression significantly increased IL-1beta and IL-18 levels as well as the expression of USP7, NLRP3, GSDMD-N, active caspase-1, pro-caspase-1, MMP1, and MMP13, which was decreased by USP7 KD or apocynin (XREF_FIG)."

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"Furthermore, our results showed that CSE mediated the increase of USP7 protein level, which eventually led to the increase of p300 protein level."