IndraLab

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USP47 deubiquitinates SNAI1. 3 / 3
1 | 2

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"USP47 has been shown to induce the decomposition of E-cadherin and promote the epithelial–mesenchymal transition via Snail-deubiquitination (Choi et al., 2017)."

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"USP47, which deubiquitinates SNAIL1, is upregulated in hypoxia via a transcription factor cascade."

"Hypoxia induces epithelial-mesenchymal transition in colorectal cancer cells through ubiquitin-specific protease 47-mediated stabilization of Snail: A potential role of Sox9"