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NLRP3 inhibits YOD1. 1 / 1
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"In addition, YOD1-mediated coagulation in MRSA-induced sepsis was blocked by the administration of MCC950, a highly potent and specific inhibitor of NLRP3, which supported that YOD1-regulated NLRP3 inflammasome-dependent coagulation in the process of MRSA-induced DIC.In general, the deubiquitination of NLRP3 promotes its activation."