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OTUD1 deubiquitinates K48- on K63. 2 / 2
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"Song et al. showed that OTUD1 binds IREB2 through the N-terminal APGR, and deubiquitinates K48- and K63-linked ubiquitin chains from IREB2."
36829909
reach
"Indeed, OTUD1 associates with the C-terminal MH2 domain of SMAD3 and deubiquitinates K48- and K63 ubiquitin chains from SMAD3, thus, contributing to SMAD3 activity, SMAD3/SMAD4 complex formation, and nuclear translocation (Figure 6D)."
36829909