IndraLab

Statements


USP5 leads to the deubiquitination of MAF. 3 / 3
1 | 2

"Consistent with the high level of c-<span class="match term1">Maf</span> protein in MM cells, <span class="match term0">USP5</span> was also highly expressed."

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"C-Maf ubiquitination can be reversed by the deubiquitinase USP5 because USP5 prevents c-Maf from polyubiquitination and degradation [XREF_BIBR]."

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"Because USP5, as a deubiquitinase of c-Maf, binds to and suppresses c-Maf polyubiquitination, we sought to determine whether mebendazole could interfere with the association of c-Maf and USP5."