IndraLab

Statements


COPS6 inhibits CDKN1B. 3 / 3
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"CSN6 mediated p27 degradation depends on the nuclear export of p27, which is regulated through COP1 's nuclear exporting signal."

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"CSN6 mediated p27 degradation depends on the nuclear export of p27 (Kip1), which is regulated through COP1 nuclear exporting signal."

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"Ectopic expression of CSN6 can decrease the expression of p27 (Kip1), while CSN6 knockdown leads to p27 (Kip1) stabilization."