IndraLab

Statements


TNFAIP3 deubiquitinates TRAF6. 3 / 5
1 1 | 3

reach
"Flagellin upregulated TNFAIP3, which blocks TRAF6 ubiquitination and inhibits the activation of NF-κB (43), at least up to 24 hours after treatment."

reach
"At the level of proximal signaling, examples are Myd88s that acts as an Myd88 antagonist ( Burns et al., 2003 ; Janssens et al., 2003 ); IRAK-M that inhibits phosphorylation of IRAK1 ( Kobayashi et al[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"For example, TNFAIP3, CYLD, USP3, USP4, USP15, USP25, and OTUD5 deubiquitinate key components of the IFN production pathway, including RIG-I, TRAF2, TRAF3, TRAF6, RIP1, and TRIF (reviewed in [93,94])."