IndraLab

Statements


USP11 increases the amount of NONO. 6 / 6
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"As a result, the knockdown of USP11 decreases NONO levels."

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"Whereas, overexpression of USP11 increases NONO levels in a dose dependent manner."

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"As a result, USP11 positively regulated NONO levels by protecting it from ubiquitin dependent degradation."

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"As a result, exogenous USP11 increased NONO levels by preventing its ubiquitination."

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"By contrast, knockdown of USP11 decreased NONO levels, which was accompanied by increased ubiquitination."

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"For example, Feng et al. discovered that USP11 promotes melanoma progression by stabilizing the protein level of NONO through deubiquitination (Feng et al., 2021)."