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NciLT inhibits USP18. 1 / 1

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"In addition, protumor interferon-stimulated genes ISG15 and IFIT3 (interferon-induced protein with tetratricopeptide repeats 3), and oncoprotein USP18 (Ubiquitin Specific Peptidase 18), which suppresses IFN responses, were also driven by LTβR-nonclassical signaling, downregulated by nciLT, and diminished in NIK-deficient B16F10 cells (Fig. 5a)."

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NciLT inhibits USP18. 1 / 1

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