IndraLab

Statements

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"Lastly, the LZ-CAM system will undoubtedly reduce laboratory resources by improving turnaround times from a 2–3-day ELISA to the 40-minute run time of this random-access and automated platform."
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"To add to these data, we compare the Liaison® XL Zika Capture IgM kit (317130D; Diasorin Inc., Saluggia, Italy, hereafter referred to as LZ-CAM) to the current gold-standard MAC-ELISA."
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"Samples were blindly tested on the LZ-CAM assay according to the manufacturer’s instructions on a LIAISON® XL Analyzer at Cadham Provincial Laboratory (Winnipeg, Manitoba, Canada)."
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"The LZ-CAM showed a sensitivity of 85% (23/27 true positives) for PRNT-confirmed ZIKV samples when compared to the in-house assays ( Tables 1 and 2 )."
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"Sensitivity of the LZ-CAM dropped to 74% when RT-PCR–confirmed ZIKV cases were included in the analysis ( Tables 1 and 2 )."
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"While both tests showed 100% specificity for Zika-negative samples (data not shown), the LZ-CAM showed a lower degree of cross-reactivity with DENV than the MAC-ELISA ( Tables 1 and 2 )."
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"Our findings indicate that the LZ-CAM assay shows comparable sensitivity and improved specificity over the currently recommended procedures."
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