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OTUD4 activates Mice. 3 / 3
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"We found that the depletion of OTUD4 in MDA-MB-231 cells markedly suppresses lung colonization in these mice, as determined by intensity of bioluminescence ( Fig. 5 H and I) and number of lung nodules[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"OTUD4 contributes to the GBM progression in mice."

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"The expression of NOD-like receptor pyrin domain containing 3 (NLRP3) and toll- like-receptor-4 (TLR4) was assayed by IHC in the lungs and intestine in HIN1 virus-induced mice to evaluate the whole efficacy of the protective effects on lungs and intestines."