IndraLab

Statements

Calcium(2+) activates CACNA1C. 2 / 3
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"The expression of functionally different splice isoforms of Ca V 1.2 and Ca V 1.3 in different tissues enables Cacna1c and Cacna1d genes to support a wider range of calcium dependent cellular functions [XREF_BIBR, XREF_BIBR, XREF_BIBR - XREF_BIBR]."
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"Timothy Syndrome, a disorder encompassing multiple dysfunctions including autistic phenotypes, can be caused by a mutation in Ca V 1.2 (CACNA1C), which increases the open times of VSCCs."
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