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USP14 inhibits Ubiquitination. 2 / 2

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"In the present study , we have revealed that repression of USP14 sensitizes vemurafenib resistance in melanoma through a previously unappreciated mechanism that USP14 but not UCHL5 stabilizes Skp2 , blocking its ubiquitination ."

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eidos

"The inhibition of USP14 can also increase the degree of ubiquitination of Dvl and significantly inhibit the downstream of Wnt signal transduction [ 18 ] ."

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USP14 inhibits Ubiquitination. 2 / 2

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