IndraLab

Statements

USP46 binds DTL and E6. 3 / 3
| 3
sparser
"In Hela cells, E6 is associates with E6AP and p53, and now we find that the E6 protein also associates with USP46 and Cdt2."
30415951
sparser
"The elution profile also suggests that the Cdt2 associates with E6-USP46, as a low-affinity substoichiometric substrate rather than as a core member of the E6-USP46 complex."
30415951
sparser
"We propose that the E6-USP46 interaction promotes the tripartite E6-USP46-Cdt2 complex either due to allosteric changes in USP46, or because Cdt2 interacts simultaneously with sites on E6 and USP46 ( xref )."
30415951