IndraLab

Statements


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reach
"The MIM 1 sequence motif responsible for VPS4 interaction [XREF_BIBR] overlaps with the CHMP3-AMSH binding site and superpositioning of the VPS4A-CHMP1B and VPS4B-CHMP2A structures with AMSH-CHMP3 demonstrates the overlap of the binding motifs, which prohibits simultaneous binding of AMSH and VPS4 to CHMP3."