IndraLab

Statements



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"Recent studies have demonstrated that FAM134B inhibits colon cancer cells proliferation, migration, wound healing, colony formation and tumour formation in vivo [21,39] ."

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"USP9X silencing upregulated the proliferation rate only on day 5, with no significant effect on the cell cycle progression."

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"Down-regulation of Usp9X inhibits proliferation in glioblastoma cell lines."

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"USP9X depletion decreases the proliferation of ReNcell VM cells but does not result in morphological changes, apoptosis or differentiation."

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"Overexpression of FAM46C inhibited cell proliferation, induced G1 phase arrest and promoted apoptosis."

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"Transient depletion of ZBTB38 or USP9X combined with decitabine exposure causes a long-term arrest of leukemia cell proliferation."

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"USP9X null neurospheres have reduced neural progenitor proliferation but not stem cell self-renewal."

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"FAM 110C protein was reported to inhibit cell proliferation by inducing G1/S arrest."

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"In colorectal cancer, USP9x can suppresses proliferation of cancer cells through stabilizing FBW7 [ 18 ]."

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"Importantly, knockdown of EGLN3 impaired USP9X mediated suppression of proliferation."

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"Knockdown of USP9X suppresses cell proliferation, inhibits G1/S phase conversion, and induces apoptosis in U251 and A172 cells."

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"In addition, depletion of USP9X decreases breast cancer proliferation, tumorigenesis, and chemoresistance in a YAP1 dependent manner."

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"USP9X knockdown restored the effects of LPS on WI-38 cell proliferation, apoptosis, inflammation, and oxidative stress, but these effects of USP9X knockdown were further abolished by TBL1XR1 overexpression."

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"Moreover, we found that knockdown of USP9x or using USP9x inhibitor can inhibit cell proliferation, which could be rescued by overexpression of SOX2."

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"Depletion of USP9X led to decreased cell proliferation (XREF_FIG), while depletion of both USP9X and YAP1 did not cause a further decrease in cell proliferation compared with cells depleted of YAP1 alone."

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"CCND1 overexpression increased USP9X knockdown-caused cell proliferation and cycle, suggesting that USP9X affects cell proliferation and cycle through CCND1."

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"However, compared with CCND1 WT, CCND1 T286A further promoted the USP9X knockdown-mediated cell proliferation and cycle, indicating that USP9X regulates cell proliferation and cycle by preventing degradation of CCND1 via the removal of conjugated ubiquitin."

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"The depletion of USP9X promotes the proliferation, migration, and invading abilities of PCa cells; these invasion and migration abilities are greater than the proliferation ability."

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"Knockdown of USP9X suppresses cell proliferation, inhibits G1/S phase conversion, and induces apoptosis in U251 and A172 cells."

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"Knockdown of USP9X inhibited cell proliferation and cell cycle progression and increased apoptosis."

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"Proliferation, migration and invasion of osteosarcoma cells were inhibited by down-regulation of USP9X, and were related to the ERK1/2 and PI3K/Akt signaling pathways, therefore, it might probably become a new target for the prevention and treatment of osteosarcoma."

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"The cell proliferation assay demonstrated that USP9X depletion increased the rate of cell proliferation in the prostate cancer cell lines only on day 5 (LNCaP, 21% increase; and PC-3, 28% increase; P<0.001 vs. siControl of the same day; n=3; Fig. 2D), which was not considered to be a notable overall effect."

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"Knockdown of FAM196B Inhibited Cell Proliferation of A549and H1299 cell lines."