IndraLab

Statements

USP9X decreases the amount of MCL1. 4 / 8
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"Moreover, knock-down of Usp9X or Bag3 depleted endogenous Mcl-1 protein levels and in turn enhanced apoptosis induced through Bcl-2 and Bcl-xL inhibition."
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"Figure 1e) and Mcl-1 levels were assessed by Western blot after 24 and 48 h. Usp9X interference decreased endogenous Mcl-1 protein levels at both concentrations after treatment for 48 h (Suppl."
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"Usp9x siRNA transfection downregulated Mcl-1 levels and increased the activated levels of apoptosis related proteins (caspase-9, caspase-3 and PARP) (XREF_FIG)."
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"We also observed that Usp9x KD decreased Mcl-1 levels in MIAPACA2 cells but increased Mcl-1 levels in 8041 cells."
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