IndraLab

Statements


OTUD5 inhibits DDX58. 3 / 3
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"For example, DUBA, a member of the Otubain (OTUB) family, has been shown to deubiquitinate TRAF3 and negatively regulate TLR3- and RIG-I/MDA5-mediated IFN induction (52)."

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"For example, DUBA, a member of the Otubain (OTUB) family, has been shown to deubiquitinate TRAF3 and negatively regulate TLR3- and RIG-I and MDA5-mediated IFN induction."

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"In addition, A20, NLRX1, PIN1, DUBA and Triad3A deregulate RIG-I mediated signaling by inhibiting MAVS, IRF3 and TRAF3."