IndraLab

Statements

Neurodegenerative Diseases activates ATXN3. 3 / 3
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"Polyglutamine expansion in Ataxin 3 causes SCA3, one of the polyglutamine-mediated neurodegenerative disorders characterized by the loss of cells in several regions of the brain stem and cerebellum [4[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disease caused by expansion of a glutamine-encoding CAG repeat in the ATXN3 gene."
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"Machado-Joseph disease (MJD) is a dominant neurodegenerative disease caused by an expanded CAG repeat in the ATXN3 gene encoding the ataxin-3 protein."
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