IndraLab

Statements

JOSD2 activates positive regulation of NF-kappaB transcription factor activity. 1 / 1

| 1

reach

"Furthermore, compared to the wide-type IMPDH2, the ubiquitination level of IMPDH2-K134R mutant was significantly reduced and JOSD2 failed to further deubiquitinate IMPDH2-K134R mutant, indicating that K134 in IMPDH2 is essential for ubiquitination and JOSD2-mediated deubiquitination (Fig. S9B).3.7 JOSD2 inhibits the activity of IMPDH2 to suppress downstream NF-kappaB activation."

40177575

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

JOSD2 activates positive regulation of NF-kappaB transcription factor activity. 1 / 1

INDRA sources:

Databases

Reading