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Cycloheximide inhibits IFNB1. 2 / 2
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"The protein synthesis inhibitor cycloheximide (CHX) totally prevented the appearance of both IFN-alpha and IFN-beta mRNA, also in cultures supplemented with a conditioned medium (CM) assumed to contain soluble factors necessary for the IFN induction."
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"Furthermore, de novo protein synthesis was also required for IFN-β induction by JEV or DEN-2, because treatment with cycloheximide, a protein synthesis inhibitor, blocked the induction of IFN-β by the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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