IndraLab

Statements



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"As examples, USP33 was down-regulated in lung cancer patients and correlated with poor prognosis, inhibiting lung cancer cell migration through stabilization of the Robo1 protein (Wen et al. 2014)."

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"In addition, USP33 also inhibits breast cancer cell migration via regulating Slit signaling [ 35 ]."

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"Similarly, the downregulation of USP33 (a ubiquitin ligase enzyme) reduces the stability of the ROBO1 receptor in lung cancer cells 29 and breast cancer cell migration 30."