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OTUD4 inhibits MYD88. 1 / 1

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"Although it was also recently reported that another deubiquitinase, OTUD4, negatively regulates NF‐κB signaling by cleaving the K63‐linked polyubiquitin chains on MyD88 (Zhao et al, 2018), only USP3 plays a critical role in innate immune tolerance, likely because of its unique (spatial and temporal) type of regulation after NF‐κB signaling activation."

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IndraLab

Statements

OTUD4 inhibits MYD88. 1 / 1

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