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USP19 inhibits TLR3. 1 / 1
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"These results suggest that USP19 impairs the association of TRIF with TLR3 after TLR3 activation in a deubiquitinating enzymatic activity dependent manner.Similarly, we found that overexpression of USP19 but not USP19(C607S) inhibited the association between TRIF and TLR4 (Fig. 6d)."