IndraLab

Statements

USP5 deubiquitinates WT1. 5 / 6
1 | 5
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"Specifically, overexpression of USP5 (a ubiquitin-specific protease) leads to the deubiquitination of the WT1 protein and increased WT1 expression, suppressing E-calmodulin expression and promoting cancer metastasis."
39672002
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"USP5 deubiquitinates the tumor suppressor Wilms tumor 1 (WT1) and promotes cell proliferation [162]."
35884607
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"We further identified that USP5 deubiquitinated WT1 and stabilized its expression."
31845546
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"Co-IP results showed that p62 deletion increased the level of ubiquitin-specific peptidase 5 (USP5), which blocked the ubiquitination of WT1."
38763964
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"Once p62 level is reduced, the highly expressed USP5 deubiquitinated WT1 to prevent WT1 degradation."
38763964