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BAP1 deubiquitinates H2Aub. 11 / 11
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"BAP1 deubiquitinates H2Aub."
29113987
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"In conclusion, we found that BAP1 can deubiquitinate H2Aub and induces radioresistance in HNSCC cells via modulation of HR."
29113987
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"Other studies in mammalian cells have also shown that BAP1 represses the expression of some target genes with BAP1 dependent deubiquitination of H2Aub on the corresponding gene promoters XREF_BIBR, XREF_BIBR."
30202049
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"BAP1 deubiquitinates histone 2A (H2Aub) on the SLC7A11 promoter and represses SLC7A11 expression in a p53-independent way (39, 40)."
39290692
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"At the SLC7A11 promoter, BAP1 deubiquitinates H2Aub and subsequently inhibits the expression of SLC7A11."
34992680
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"10 Deubiquitination of HCF1 and H2Aub by BAP1 promotes their association with EF2, YY-1, and FoxK2, which regulate cell-cycle progression, cell proliferation and cell-cycle control."
35317997
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"Although USP16 is clearly demonstrated to facilitate transcriptional regulation in this manner, BRCA1-associated protein 1 (BAP1), a member of the UCH family of DUBs, can also deubiquitinate H2Aub and regulate transcription, implying a degree of redundancy [66,67]."
36980227
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"These results suggest that HG inhibits SLC7A11 function by promoting BAP1 expression, thereby inducing ferroptosis in podocytes.3.5 HG promotes ferroptosis by promoting BAP1 deubiquitination of H2Aub on SLC7A11."
39816499
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"BAP1 has been shown to induce deubiquitination of H2Aub on the SLC7A11 promoter."
38816686
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"According to a report by Zhang et al., BAP1 causes the deubiquitination of H2Aub, which prevents SLC7A11 from being expressed [14]."
38816686
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"A recent study reported that BAP1 inhibits cystine uptake and makes cells more susceptible to ferroptosis by deubiquitinating H2Aub on SLC7A11."
37552314