IndraLab

Statements


EV71 activates USP19. 2 / 2
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"Furthermore, EV71 infection induces the upregulation of USP19 which negatively regulates cellular antiviral type I interferon signaling by targeting the tumor necrosis receptor associated factor 3 (TRAF3) molecule and decreasing TRAF3 ubiquitination of K63-linkage [18]."

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"Previous studies have indicated that EV71 infection induces the up-regulation of USP19, which negatively regulates the antiviral type I interferon signalling by removing K-63 polyubiquitin chains from TRAF3 35."